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Assignment Questions

Endocrine Pancreas

CASE STUDY: A 62 yr. old African-American male with a long history of obesity, diabetes, dyslipidemia presented to the hospital emergency department with a 6-day history of weakness, unusual thirst, dizziness, constant urination, extreme tiredness, nausea, vomiting and abdominal pain. His diabetes has been managed in the past with diet alone. On examination, his temp was 99.1°F, BP 90/60 mm Hg, pulse was 136, respiratory rate 36. Lab results revealed:

Room air arterial blood gas with a ph of 7.12, PCO2 17 mmHg, and a bicarbonate of 5.6 mEq/l
Urinalysis 4+ glucose and 3+ ketones
Chemistry panel: glucose, 420 mg/dl; BUN, 16 mg/dl; creatinine, 1.3 mg/dl; sodium, 139 mEq/L; chloride, 112 mEq/L.

(Source: adapted from F.C., graduate nursing student)

Question. Based on the above information, and on additional material researched, suggest a possible diagnosis for this condition, JUSTIFY your opinion by explaining (in detail) the pathophysiology of the chosen disease process.

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