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Assignment Questions

Mechanisms and techniques of the Knockout Mice experiments

I would like for the paper to explore the mechanisms and techniques of the Knockout Mice experiments: how they are performed and how they affect the mice at the cellular level in terms of cell structure and/or function. I also would like one or two examples described of experiments in which Knockout Mice have been used in the study of diabetes. The paper should focus mainly on the cell biology rather than genetics or the biology of the entire organism, though necessary references to those may obviously be made.

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